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簡要描述：c-Kit is a transmembrane tyrosine kinase encoded by the cKit proto oncogene. c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, and activation. Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, gastrointe
產(chǎn)品型號：bs-10005R-PE廠商性質(zhì)：生產(chǎn)廠家更新時間：2025-03-06訪 問 量： 69詳細介紹
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