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簡要描述：This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1. PubMed:12138094 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin
產(chǎn)品型號(hào)：bs-0227R-PE廠商性質(zhì)：生產(chǎn)廠家更新時(shí)間：2025-03-05訪 問 量： 49產(chǎn)品分類
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